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Join PacBio webinar to discover how short-read sequencing system Onso with Q40+ accuracy is allowing cancer researchers to detect rare genetic variants below the limit of detection, and how sequencing by binding (SBB) technology can increase sensitiv...

Take your research to new heights by participating in the Asia-Pacific exclusive Onso SBB Grant. Be at the forefront of a revolution in short-read sequencing's accuracy with the PacBio Onso system....

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Researchers now have a choice when they want to look at protein-DNA interactions on a specific gene or across the genome. Two options include Chromatin Immunoprecipitation (ChIP) and CUT&RUN (Cleavage Under Targets & Release Using Nuclease), which a...

Join this webinar to learn about building the first isoform-resolution colorectal cancer (CRC) transcriptomic atlas / Characterizing genes and isoforms associated with different epithelial lineages and subpopulations / An algorithm to identify recurr...

谷氨酰胺合成酶（GS）可以促進谷氨酰胺的合成進而促進蛋白質和核苷酸的合成以及腫瘤細胞生長，因此GS通常被認為是促癌的。然而在有β-Catenin激活的小鼠肝癌模型中敲除肝臟GS卻顯著促進了肝腫瘤生長。在機理方面，在肝臟中特異性敲除GS加劇了高氨血症並促進了非必需氨基酸合成，進而激活了mTORC1。 mTORC1和谷氨酸轉氨酶的藥物抑制和肝臟特異性敲除均抑制了GS敲除促進的肝腫瘤生長。因此，GS介導的氨清除在存在β-Catenin激活突變的肝臟中可抑制肝腫瘤生長。...

Arthur Dondi, PhD student in computational biology, ETH Zürich Zhu Tingting, Bioinformatics Scientist, Field Application, Asia Pacific PacBio Join this webinar to hear about how long-read sequencing (HiFi sequencing) enables isoforms identification ...

免疫熒光顯微成像的發展已有數十年之久，在傳統細胞生物學領域幫忙科學家們探索了許多未知的洞見。近年來，在腫瘤免疫領域興起的多組學技術，免疫熒光顯微成像的方法在保證組織原位性的前提之下，獲取了大量腫瘤微環境的空間信息，極大地豐富了科學家們對於腫瘤微環境的認識。...

本講座首先將簡要介紹Hippo通路不同元件的發現過程，接著講述課題組在Hippo通路分子架構方面的研究，特別是HPO1和HPO2”雙模塊”新模型的提出及其在肝臟發育和腫瘤發生中的功能，最後將探討靶向Hippo信號通路的新方法。...

Join this webinar to hear about how HiFi long-read sequencing is energizing the potential of population genomics by enabling scientists to: Catalogue all genetic variation, reflecting a population’s true diversity. Maximize discovery potential to ena...

Have you ever concerned of potential power shortage and failure in ultra-low temperature refrigerator, leading to the deterioration of precious samples and reagents? The miracle ice slab ChillLabo is here to rescue! Compared to dry ice, it is more ...

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As agricultural industries key in on sustainability efforts, it’s imperative to consider how to improve upon the efficiency of our “original recycling,” rendering. The weight of serving as a recyclable industry all while enduring the costs that come ...