Home > Virtual Demo > Saphyr System

Saphyr System

2020-08-14 19:43:25    Source:Gene Company Limited

Saphyr - BioNano Genomics | accela

Bionano Genomics Saphyr® System is a genome imaging tool for optical mapping to achieve high-speed, high-throughput structural variant detection and analysis with exceptional sensitivity and specificity. 


Scaffold Bionano genome mapping data with sequencing data to dramatically improve assembly contiguity, reduce sequencing coverage needed, and automatically correct errors in sequencing-based assemblies.

Saphyr Genome Mapping | Bionano Genomics

Bionano Saphyr Chip® linearize DNA, enabling high-speed, high-throughput genome mapping and structural variation detection for a variety of applications including human and clinical research.


Please Click Content, media, music, play, sign, video icon to watch a quick demonstration of loading DNA sample on Bionano Saphyr Chip®.

Bionano Prep Kits - Bionano Genomics


Bionano Prep Kits™ provide the critical reagents and protocols needed to extract and label high molecular weight (HMW) DNA for use on the Saphyr™ genome mapping systems. Bionano kits are optimized for performing Bionano genome mapping applications on a variety of sample types.


Please Click Content, media, music, play, sign, video icon to watch a quick demonstration of some procedures of Bionano Prep SP Frozen Human Blood DNA Isolation.
Please Click Content, media, music, play, sign, video icon to watch some quick demonstrations of pellet resuspension, tissue disruption, density gradient, transfer Nuclei band and liquid nitrogen grinding steps in Bionano Prep Plant DNA Isolation.


1598609316269263.png


The reagents of Bionano Prep™ DNA Labeling Kit - Direct Label and Stain (DLS) are used specifically for applications on Saphyr systems. Specific sequence motifs are labeled directly with fluorophores in a single enzymatic reaction on high-molecular-weight DNA purified using the appropriate Bionano DNA Isolation Kit. DLS results in uniquely identifiable genome-specific label patterns on the double stranded genomic DNA that enable de novo map assembly, anchoring of sequence contigs, and discovery of structural variation (> 500 bp).


Please Click Content, media, music, play, sign, video icon to watch a quick demonstration of mixing viscous gDNA with DLS master mix.